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Publications & Presentations

Textbooks:

Leonard, Michael S. Organic Chemistry and Solutions Manual for Organic Chemistry, First Edition: 2015.

• The textbook and solutions manual are available as free PDF downloads from https://gum.co/organicchemistry (simply enter $0 in the price field).

 

Leonard, Michael S. Introductory Organic Reaction Mechanisms: A color-coded approach to arrow pushing, First Edition; Lulu: 2013.

• For a mission statement for the text see the “Introductory Organic Reaction Mechanisms Textbook” link on my homepage (http://wiki.washjeff.edu/display/MSL/Home) or the publisher’s page: (http://www.lulu.com/shop/michael-leonard/introductory-organic-reaction-mechanisms-a-color-coded-approach-to-arrow-pushing/paperback/product-21240857.html).

• The textbook is also available as an e-book on Scribd (http://www.scribd.com/doc/174107198/Introductory-Organic-Reaction-Mechanisms-A-color-coded-approach-to-arrow-pushing).

• The text is also available on Amazon (http://amzn.com/1304515893).

• The text is accompanied by a YouTube channel in which each of the 80 mechanisms in the book is presented over the course of 80 brief videos (http://www.youtube.com/user/OrganicMechanisms).

 

Leonard, Michael S. Intermediate Organic Chemistry, First Edition; Lulu: 2013.

• For a mission statement for the text see the “Intermediate Organic Chemistry Textbook” link on my homepage (http://wiki.washjeff.edu/display/MSL/Home) or the publisher’s page: (http://www.lulu.com/shop/michael-leonard/intermediate-organic-chemistry/paperback/product-21107718.html).

• The textbook is also available as an e-book on Scribd (http://www.scribd.com/doc/152768407/Intermediate-Organic-Chemistry).

• The text is also available on Amazon (http://amzn.com/1304217566).

Publication on curriculum development:

• Malinak, S. M.; Bayline, J. L.; Brletic, P. A.; Harris, M. F.; Iuliucci, R. J.; Leonard, M. S.; Matsuno, N.; Pallack, L. A.; Stringfield, T. W.; Sunderland, D. P. “The Impacts of an ‘Organic First’ Chemistry Curriculum at a Liberal Arts College.” J. Chem. Educ. 2014, ASAP.

Publications resulting from research with W&J College students and Project SEED outreach students:

• Leonard, M. S. "The aporhoeadane alkaloids." Archive for Organic Chemistry (ARKIVOC), 2013 (i) 1-65.

• Piko, B. E.; Keegan, A. L.; Leonard, M. S. “A concise synthesis of the aporhoeadane skeleton.” Tetrahedron Lett. 2011, 52(16), 1981-1982.

Carbaugh, A. D.; Vosburg, W.; Scherer, T. J.; Castillo, C. E.; Christianson, M. A.; Kostarellas, J.; Gosai, S. J.; Leonard, M. S. “A concise synthesis of substituted benzoates.” Archive for Organic Chemistry (Arkivoc), 2007 (xii) 43-54.

Tomasevich, L. L.; Kennedy, N. M.; Zitelli, S. M.; Hull, R. T., II; Gillen, C. R.; Lam, S. K.; Baker, N. J.; Rohanna, J. C.; Conley, J. M.; Guerra, M. L.; Starr, M. L.; Sever, J. B.; Carroll, P. J.; Leonard, M. S. “Ninhydrin as a building block for yohimbanones, β-carbolines, and oxyprotoberberines.” Tetrahedron Lett. 2007, 48(4), 599-602.

Presentations and local chemical news articles resulting from research with W&J College students and Project SEED outreach students:

Wytovich, S. A.; Leonard, M. S. “Construction of the Choi framework.” Abstracts of Papers, 249th National Meeting of the American Chemical Society, Denver, CO, March 22-26, 2015; American Chemical Society: Washington, D.C., 2015; CHED 1259.

Tropp, J.; Leonard, M. S. “Progress toward the synthesis of the Choi framework.” Abstracts of Papers, 2014 Central Regional Meeting of the American Chemical Society, Pittsburgh, PA, October 29-November 1, 2014; American Chemical Society: Washington, D.C., 2014.

Pingitore, A. T.; Leonard, M. S. “Hammett study of the transesterification of para-nitrophenyl benzoates.” Abstracts of Papers, 247th National Meeting of the American Chemical Society, Dallas, TX, March 16-20, 2014; American Chemical Society: Washington, D.C., 2014; CHED 1041.

• Stultz, E. T.; Leonard, M. S. “Progress toward the synthesis of poison dart frog alkaloid 237I.” Abstracts of Papers, Duquesne University Undergraduate Research Symposium, July 29, 2011.

• Warmbrodt, T. A.; Leonard, M. S. “Progress toward the synthesis of poison dart frog alkaloid 245F.” Abstracts of Papers, Duquesne University Undergraduate Research Symposium, July 29, 2011.

Piko, B. E.; Leonard, M. S. “Studies directed toward the total synthesis of chilenine.” Abstracts of Papers, 239th National Meeting of the American Chemical Society, San Francisco, CA, March 21-25, 2010; American Chemical Society: Washington, D.C., 2010; CHED 937.

Piko, B. E.; Leonard, M. S. “Studies directed toward the total synthesis of chilenine.” Abstracts of Papers, Duquesne University Undergraduate Research Symposium, July 31, 2009.

Switzer, A. M.; Leonard, M. S. “Total synthesis of lunamarine and analogues.” Abstracts of Papers, Duquesne University Undergraduate Research Symposium, July 31, 2009.

Leonard, M. S. “Synthetic organic research with undergraduate students at Washington and Jefferson College.” Abstracts of Papers, 237th National Meeting of the American Chemical Society, Salt Lake City, UT, March 22-26, 2009; American Chemical Society: Washington, D.C., 2009; CHED 105.

Amos, L. K.; Leonard, M. S. “Studies toward the synthesis of lunamarine.” Abstracts of Papers, 237th National Meeting of the American Chemical Society, Salt Lake City, UT, March 22-26, 2009; American Chemical Society: Washington, D.C., 2009; CHED 860.

Tomasevich, L. L.; Leonard, M. S. “An Intermolecular Conjugate Addition Approach to the Synthesis of Lunamarine.” Abstracts of Papers, 235th National Meeting of the American Chemical Society, New Orleans, LA, April 6-10, 2008; American Chemical Society: Washington, D.C., 2008; CHED 652.

Amos, L. K.; Leonard, M. S. “An Intramolecular Conjugate Addition Approach to the Synthesis of Lunamarine.” Abstracts of Papers, 235th National Meeting of the American Chemical Society, New Orleans, LA, April 6-10, 2008; American Chemical Society: Washington, D.C., 2008; CHED 653.

Graf, N. J.; Leonard, M. S. “An Intramolecular Conjugate Addition Approach to the Synthesis of Lunamarine Congeners.” Abstracts of Papers, 235th National Meeting of the American Chemical Society, New Orleans, LA, April 6-10, 2008; American Chemical Society: Washington, D.C., 2008; CHED 654.

Lloyd, K. R.; Leonard, M. S. “Effects of steric hindrance on a key cyclization in the synthesis of the alkaloid lunamarine.” Abstracts of Papers, 235th National Meeting of the American Chemical Society, New Orleans, LA, April 6-10, 2008; American Chemical Society: Washington, D.C., 2008; CHED 589.

Leonard, M. S. “Project SEED in its Fourth Year at Washington & Jefferson College.” The Crucible, 2007, XCIII(1), 3.

Tomasevich, L. L.; Leonard, M. S. “An Intermolecular Conjugate Addition Approach to the Synthesis of Lunamarine.” Abstracts of Papers, Duquesne University Undergraduate Research Symposium, July 27, 2007.

Amos, L. K.; Leonard, M. S. “An Intramolecular Conjugate Addition Approach to the Synthesis of Lunamarine.” Abstracts of Papers, Duquesne University Undergraduate Research Symposium, July 27, 2007.

Graf, N. J.; Leonard, M. S. “An Intramolecular Conjugate Addition Approach to the Synthesis of Lunamarine Congeners.” Abstracts of Papers, Duquesne University Undergraduate Research Symposium, July 27, 2007.

Jolly, D.; Leonard, M. S. “A Study of the Heck Reaction, a Key Step in the Synthesis of Lunamarine Congeners.” Abstracts of Papers, Duquesne University Undergraduate Research Symposium, July 27, 2007.

Leonard, M. S. “Project SEED Student Co-Authors Research Paper.” The Crucible, 2007, XCII(8), 1.

Tomasevich, L. L.; Leonard, M. S. “Synthesis of novel resorcinol derivatives via fragmentation of Meldrum’s acid adducts” Abstracts of Papers, 233rd National Meeting of the American Chemical Society, Chicago, IL, March 25-29, 2007; American Chemical Society: Washington, D.C., 2007; CHED 776.

Kennedy, N. M.; Zitelli, S. M.; Leonard, M. S. “Synthesis of yohimbanones and beta-carbolines through heterocyclic rearrangement chemistry” Abstracts of Papers, 233rd National Meeting of the American Chemical Society, Chicago, IL, March 25-29, 2007; American Chemical Society: Washington, D.C., 2007; CHED 778.

Carbaugh, A. D.; Leonard, M. S. “Synthetic approaches to 4-(hydroxymethyl)benzoates and cyclophanes” Abstracts of Papers, 233rd National Meeting of the American Chemical Society, Chicago, IL, March 25-29, 2007; American Chemical Society: Washington, D.C., 2007; CHED 779.

Leonard, M. S. “Project SEED in its Third Year at Washington & Jefferson College.” The Crucible, 2006, XCII(3), 1 & 12.

            This article was subsequently published in ChemunityNews, November 2006.

Carbaugh, A. D.; Leonard, M. S. “Synthetic Approaches to 4-(Hydroxymethyl)benzoates and Cyclophanes.” Abstracts of Papers, Duquesne University Undergraduate Research Symposium, July 28, 2006.

Hull, R. T.; Leonard, M. S. “A Concise Synthesis of 1,3-Disubstituted Beta-Carbolines.” Abstracts of Papers, Duquesne University Undergraduate Research Symposium, July 28, 2006.

Tomasevich, L. L.; Leonard, M. S. “Synthesis of Novel Resorcinol Derivatives via Fragmentation of Meldrum’s Acid Adducts.” Abstracts of Papers, Duquesne University Undergraduate Research Symposium, July 28, 2006.

Leonard, M. S. “The Second Year of Project SEED at Washington & Jefferson College.” The Crucible, 2005, XCI(2), 2.

Gillen, C. R.; Hull, R. T.; Kennedy, N. M.; Leonard, M. S. “Investigation of Novel Routes to Common Heterocyclic Ring Systems.” Abstracts of Papers, Duquesne University Undergraduate Research Symposium, July 29, 2005.

Rohanna, J. C.; Leonard, M. S. “Synthesis of Novel b-Carbolines by the Pictet-Spengler Reaction of Tryptophan and Ninhydrin: Oxidative Rearrangement of Yohimbanone to the Corresponding b-Carbolines.” Abstracts of Papers, 229th National Meeting of the American Chemical Society, San Diego, CA, March 13-17, 2005; American Chemical Society: Washington, DC, 2005; CHED 1159.

Leonard, M. S.; “Project SEED: The First Four Weeks.” The Crucible, 2004, LXXXX(1), 1.

Vosburg, W.; Scherer, T.; Leonard, M. S. “The Diels-Alder Reaction of Coumalic Acid Derivatives.” Abstracts of Papers, Duquesne University Undergraduate Research Symposium, July 30, 2004.

Baker, N. J.; Zitelli, S. M.; Leonard, M. S. “A Novel Route to b-Carbolines and Related Heterocycles.” Abstracts of Papers, Duquesne University Undergraduate Research Symposium, July 30, 2004.

Presentations on Curriculum Development:

Leonard, M. S. “An Intersession Science & Art Course for Non-Science Majors” Abstracts of Papers, 40th Middle Atlantic Regional Meeting (MARM) of the American Chemical Society, Queensborough Community College, NY, May 17 – 21, 2008, American Chemical Society: Washington, D.C., 2008; Chemistry & the Arts 385.

Leonard, M. S. “Enriching a science and art course for nonscience majors through polarized light microscopy” Abstracts of Papers, 234th National Meeting of the American Chemical Society, Boston, MA, August 19-23, 2007; American Chemical Society: Washington, D.C., 2007; CHED 33.

Leonard, M. S. “Science and art during the intersession: Engaging the non-science major” Abstracts of Papers, 234th National Meeting of the American Chemical Society, Boston, MA, August 19-23, 2007; American Chemical Society: Washington, D.C., 2007; CHED 377.

Interviews:

•  Interviewed for U.S. News and World Report article entitled “Take a College Road Trip”, September 1 – 8 issue, 2008, page 68.

•  Interviewed for Nature Biotechnology article about the founder of Innocentive: Wilan, K. “Profile: Alpheus Bingham” Nature Biotechnology, 2007, 25(10), 1072.

•  Interviewed for Washington Post article on crowdsourcing (related to work with Innocentive): Sipress, A. “T-Shirt Maker’s Style, Drawn From Web Users: More Firms Parcel Out Tasks Via Internet” The Washington Post, June 18, 2007, A01.

•  Interviewed for Contingent Workforce Strategies article about Innocentive: Testa, B. M. “Seeking Ideas Everywhere” Contingent Workforce Strategies, March 21, 2007.

Publications during my career at W&J that resulted from my doctoral research at the University of Pennsylvania:

Alexander, M. D.; Burkart, M. D.; Leonard, M. S.; Portonovo, P.; Liang, B.; Ding, X.; Joullié, M. M.; Gulledge, B. M.; Aggen, J. B.; Chamberlin, A. R.; Sandler, J.; Fenical, W.; Cui, J.; Gharpure, S. J.; Polosukhin, A.; Zhang, H.-R.; P. Evans, P. A.; Richardson, A. D.; Harper, M. K.; Ireland, C. M.; Vong, B. G.; Brady, T. P.; Theodorakis, E. A.; La Clair, J. J. “A Central Strategy for Converting Natural Products into Fluorescent Probes.” ChemBioChem. 2006, 7(3), 409-416. (note: contact address for Leonard, M. S. is misprinted in this article)

Leonard, M. S.; Carroll, P. J.; Joullié, M. M. “Synthesis of a Pondaplin Dimer and Trimer. Aromatic Interactions in Novel Macrocycles.” J. Org. Chem. 2004, 69(7), 2526-2531.

Leonard, M. S.; Carroll, P. J.; Joullié, M. M. “Oxidative Rearrangement of Yohimbanones.” Synth. Commun. 2004, 34(5), 863-869.

Publications & presentations during my doctoral research at the University of Pennsylvania:

Leonard, M. S.; Hauze, D. B.; Carroll, P. J.; Joullié, M. M. “Formation of Yohimbanones via a Novel Rearrangement.” Abstracts of Papers, The 36th Middle Atlantic Regional Meeting of the American Chemical Society, Princeton University, June 8-11, 2003.

Leonard, M. S.; Hauze, D. B.; Carroll, P. J.; Joullié, M. M. “Formation of Yohimbanones via a Novel Rearrangement.” Tetrahedron. 2003, 59, 6933-6936.

• Leonard, M. S.; Chen, W.-C.; Joullié, M. M. “Synthetic approaches to pondaplin and analogues.” Poster presented at 2002 Natural Products Gordon Conference, Tilton School, Tilton, NH, July 28 – Aug 2, 2002.

• Leonard, M. S.; Chen, W.-C.; Joullié, M. M. “Synthetic approaches to pondaplin and analogues.” Abstracts of Papers, 224th National Meeting of the American Chemical Society, Boston, MA, Aug 18-22, 2002; American Chemical Society: Washington, DC, 2002; ORGN 780.

• Joullié, M. M.; Leonard, M. S.; Portonovo, P.; Liang, B.; Ding, X.; LaClair, J. J. “Chemical Defense in Ascidians of the Didemnidae Family.” Bioconjugate Chem. 2003, 14, 30-37.

• Leonard, M. S.; Joullié, M. M. Pentafluorophenyl diphenylphosphinate (FDPP).  Encyclopedia of Reagents for Organic Synthesis, 2002.

• Ding, X.; Vera, M. D.; Liang, B.; Zhao, Y.; Leonard, M. S.; Joullié, M. M. “Structure-activity relationships of side-chain modified didemnins.” Bioorg. Med. Chem. Lett. 2001, 11, 231-234.

• Portonovo, P.; Ding, X.; Leonard, M. S.; Joullié, M. M. “First total synthesis of a fluorescent didemnin.” Tetrahedron 2000, 56, 3687-3690.

• Liang, B.; Portonovo, P.; Vera, M. D.; Richard, D. J.; Leonard, M. S.; Joullié, M. M. “Total syntheses and biological investigations of tamandarin compounds.” Abstracts of Papers, Part 2, 220th National Meeting of the American Chemical Society, Washington, DC, Aug 20-24, 2000; American Chemical Society: Washington, DC, 2000; ORGN 0014.

Publication from my undergraduate research at Goucher College:

 • Horn, D. E.; Leonard, M. S.; Fischl, A. J.; Gray, M.; Clark, D. W.; Averion-Mahlock, T.; Sader, C. N. “Synthesis of symmetrically substituted 1,4-bis[(aminoalkyl)amino]-5,8-dimethylanthracene-9,10-diones.” Archive for Organic Chemistry (Arkivoc),  2000 (vi) 876-881.

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